Prognosis, treatment and outcome of childhood mesangiocapillary (membranoproliferative) glomerulonephritis
نویسندگان
چکیده
منابع مشابه
Prognosis, treatment and outcome of childhood mesangiocapillary (membranoproliferative) glomerulonephritis.
BACKGROUND Prognostic factors and outcome are incompletely known in childhood mesangiocapillary glomerulonephritis (MCGN). This study aimed to correlate renal outcome with clinical and histopathological variables. METHODS We conducted a two-centre retrospective analysis of children with MCGN. RESULTS Fifty-three children presented at a mean age of 8.8 years (range: 13 months-15 years). They...
متن کاملMesangiocapillary glomerulonephritis.
The clinical and histological features of idiopathic mesangiocapillary glomerulonephritis (MCGN) have been reviewed, with a survey of the most recent literature, including the retrospective analysis of the data of the Italian Study Group of Renal Immunopathology on 368 patients. In both major types of MCGN, six morphological variants have been characterized (classical MCGN, nodular MCGN, exudat...
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A major shift in our understanding of the membranoproliferative glomerulonephritis (MPGN) lesion is the focus on which components of the complement pathway are involved in mediating renal injury. Hence, MPGN is no longer classified solely by ultrastructural findings on biopsy but instead divided into immune complex-mediated lesions versus complement-mediated lesions. This emphasis on complement...
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BACKGROUND Therapeutic approach to patients with idiopathic membranoproliferative glomerulonephritis is still controversial. Because it is more common in developing countries, the studies about it are limited. METHODS We used cyclosporine to treat 18 patients with membranoproliferative glomerulonephritis who were resistant to other treatment protocols such as using aspirin, dipyridamole, or s...
متن کاملMembranoproliferative Glomerulonephritis
Membranoproliferative glomerulonephritis (MPGN) refers to glomerular pathology in which there is thickening of the capillary wall together with mesangial expansion. In this article we firstly review the pathological features of MPGN and discuss how advances in our understanding of the association between abnormalities in the regulation of complement and MPGN have revealed limitations in the his...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2004
ISSN: 1460-2385
DOI: 10.1093/ndt/gfh484